Formulations Tim-Brim-Dor-Lat® (Timolol/Brimonidine/Dorzolamide/Latanoprost) PF* – 5mL

Tim-Brim-Dor-Lat® (Timolol/Brimonidine/Dorzolamide/Latanoprost) PF* – 5mL

(Timolol/Brimonidine/Dozolamide/Latanoprost) Preservative-Free

Not available from our FDA registered outsourcing facility. Available from our patient specific pharmacy.

Simple Drops® combine multiple medications into a single bottle. All Simple Drops® compounded formulations are preservative-free.

Click here to download the product insert for this formulation.

Classification Topical Medication
Sub-classification Solution
Strength (Concentration) common dose* 0.5/0.15/2/0.005%
Size (Volume) 5mL Dropper

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Patients may need to take more than one eye drop product pursuant to multiple dosing regimens, as directed by his or her prescriber, in order for the active ingredients to remain effective throughout the day.

*For professional use only. ImprimisRx® Pharmacy specializes in customizing medications to meet unique patient and practitioner needs. ImprimisRx® dispenses only to individually identified patients with valid prescriptions. No compounded medication is reviewed by the FDA for safety or efficacy. ImprimisRx® does not compound copies of commercially available products. References available upon request.

Potential Ingredient Risks

Storage: Store under refrigeration, 2°C to 8°C (36°F to 46°F)

Auxiliary Labeling: Store upright in original bottle, Protect from light, For professional use only.

Timolol Maleate

Possible Indications: Treatment of elevated intraocular pressure in patients with ocular hypertension or open-angle glaucoma

Possible Adverse Effects: Ocular burning/stinging on instillation, Dry eyes, Itching, Foreign body sensation, Discomfort in the eye, Eyelid erythema, Conjunctival injection, Headache, Eye pain, Epiphora, Photophobia, Blurred or abnormal vision, Corneal fluorescein staining, Keratitis, Blepharitis, Cataract, Cardiac arrythmia; palpitation; bradycardia; Syncope, heart block; cerebral vascular accident; cerebral ischemia; cardiac failure and cardiac arrest

Potential Contraindications/Precautions: Patients Less than 12 Years, Lactation, Pregnancy, Bronchial Asthma or History Of., Sinus Bradycardia, Second or Third Degree Atrioventricular Block; Overt Heart Failure;
Cardiogenic Shock.

Brimonidine Tartrate

Possible Indications: Treatment of elevated intraocular pressure in patients with ocular hypertension or open-angle glaucoma

Possible Adverse Effects: Oral dryness, Ocular hyperemia, Burning and Stinging on Instillation, Headache,
Blurred vision, Foreign body sensation, Fatigue/drowsiness, Conjunctival follicles, Ocular allergic reactions, Ocular pruritis, Corneal staining/erosion, Photophobia, Eyelid erythema, Ocular ache/pain, Upper respiratory symptoms,
Dizziness, Blepharitis, ocular irritation, Lid crusting, Conjunctival hemorrhaging, Abnormal taste, insomnia, depression,hypertension, anxiety, palpitations/arrhythmias, nasal dryness and syncope

Potential Contraindications/Precautions: Infants, Lactation, Pregnancy, Concomitant MAO Inhibitor Therapy

Dorzolamide

Possible Indications: Treatment of elevated intraocular pressure in patients with ocular hypertension or open-angle glaucoma

Possible Adverse Effects: Ocular burning, stinging, or discomfort immediately following ocular administration,
Bitter taste, Superficial punctate keratitis, Ocular allergic reaction, Conjunctivitis and lid reactions, Blurred vision,
Eye redness, Tearing, Dryness, Photophobia, Headache, Nausea, Asthenia/fatigue, Skin rashes, Urolithiasis,
Iridocyclitis

Potential Contraindications/Precautions: Neonates and Patients Less than 12 Years, Lactation, Pregnancy

Latanoprost

Possible Indications: Treatment of elevated intraocular pressure in patients with ocular hypertension or open-angle glaucoma

Possible Adverse Effects: Iris pigmentation changes, Eyelid skin darkening, Eyelash changes (increased length, thickness pigmentation and number of lashes), Iritis/uveitis, Macular edema; including cystoid macular edema, Foreign body sensation, Punctate keratitis, Stinging, Conjunctival hyperemia, Blurred vision, Itching, Burning,
Increased pigmentation of the iris, Excessive tearing, Eyelid discomfort/pain, Dry eye, Eye pain, Eyelid margin crusting, Erythema of the eye lid, Photophobia

Potential Contraindications/Precautions: Patients Less than 3 Years, Lactation, Pregnancy, Child Bearing Aged Females